Hormone Secret No. 4: Process Control

Having said all that, how exactly do hormones control the process? This is a question that everyone wants to know. In the primordial follicle stage, it is not affected by any hormones. At the pre-antral follicle stage, its development begins to depend on gonadotropins. FSH increases the number of granulosa cells and LH. As the receptors increase, the follicles begin to grow. This is the initial stage of follicular development, and the driving force for this is FSH.

FSH begins to appear in the luteal phase of the previous menstrual cycle, because estrogen and progesterone begin to decline during this period, gradually eliminating the negative feedback effect on the hypothalamus; and estrogen reaches its lowest level during the menstrual period. point, which is very conducive to the increase of FSH.

Now we know clearly that estrogen reaches a low point during the menstrual period, and such a low point must be formed to facilitate the emergence and increase of FSH. After FSH rises, follicle development is initiated. Its function is like the battery when starting a car, but the energy that makes the engine work normally is gasoline, not the battery\’s electricity. Therefore, as \”gasoline\”, estrogen should gradually increase after the menstrual period ends, and cannot stay there for a long time. Lows.

The rapid increase in estrogen accelerates the development of follicles, and the rapid development of follicles also increases the level of estrogen. Therefore, after the menstrual period, all women with slow follicular development and long follicular phase should supplement estrogen in time.

After the menstrual period ends, estrogen must rise every day, reaching about 100pg/ml. If estrogen is lower than this level, your follicular phase will be prolonged.

Now, everyone already knows the two stages of estrogen changes: that is, the low-level stage during the menstrual period and the rising stage after the menstrual period ends.

During the rising stage of estrogen, estrogen strengthens the negative feedback effect on the hypothalamus, and the FSH level decreases, thus causing most of the many follicles that have just appeared to become atretic, allowing only one of them to continue. Development, this is the wonderful arrangement of the endocrine system in the female body!

Next, comes the third stage of estrogen changes in the follicular phase.

In the few days before ovulation, estrogen reaches a peak. The height of this peak must reach more than 200pg/ml. After it exceeds 200pg/ml, the higher the better, some hospitals. This peak is set at around 550pg/ml; 200pg/ml is called the threshold of estrogen. Above this value, estrogen reverses its negative feedback effect on the hypothalamus and changes to a positive feedback state, which means that itThe increase in LH will also drive the other two hormones (LH, FSH) to increase, causing these two hormones to also reach their peak!

So before ovulation, the three hormones estrogen, LH and FSH reach their peak at the same time, fully preparing for the rupture of follicles, the discharge of eggs and the formation of the corpus luteum.

Everyone should be very clear now. Estrogen has three stages of change during the follicular phase (note, it is the follicular phase):

◎ During menstruation The lowest period;

◎ The rising period after the end of menstruation (acting as a negative feedback);

◎ The peak period before ovulation (acting as a positive feedback).

For estrogen, when it is low, it should be as low as the bottom, and when it is high, it should be as high as the peak!

When your estrogen value is very low during the menstrual period, such as around 24pg/ml; during the rising period, it remains around 100pg/ml; and during the peak period, it reaches 550pg/ml (more than 200pg/ml) . Then in the final stage, it is possible to bring LH to 100IU/L and FSH to 22 IU/L.

When these three hormones peak at the same time, it is very difficult for the follicles to develop rapidly, rupture on time and form a well-functioning corpus luteum.

We have introduced to you a very standard estrogen change curve during each menstrual cycle and the follicular phase of women. As long as your estrogen is running according to such a change pattern, you don’t have to worry. Follicle development problems. Once you find that the follicles develop slowly and the follicular phase is extremely long, at this time, if you measure estrogen, its value must be relatively low; and the usual problem of insufficient corpus luteum is most likely caused by the three hormones before ovulation. It’s because they didn’t reach the peak at the same time!

Therefore, the appropriate approach is to supplement estrogen in an appropriate amount immediately after menstruation, and to supplement estrogen in larger amounts before ovulation. This is in line with the changes in female estrogen. .

To supplement estrogen, Western medicine often uses Bujiale and Premarin; Chinese medicine often uses Ziheche; and we ourselves can completely absorb phytoestrogens from food. The foods are soy milk, royal jelly, soy isoflavones, Thai kudzu root, etc. Phytoestrogens in food only have weak estrogenic effects, so they have a two-way regulatory function and are usually harmless. As long as everyone takes them consistently, they will definitely be effective.


This article is provided by Baidu Reading and is excerpted from \”Pregnancy Can Be Simple\” Author: Feifei Mom

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